This module aims to help nurses to administer inotropic drugs in a safe, effective and patient-centred manner. The mode of action of inotropic drugs makes them well suited to treat haemodynamic compromise experienced by critically ill patients. Effects such as increased force of myocardial contraction and vasoconstriction make them highly potent. Knowledge relating to cardiovascular physiology and the mode of action of inotropes enables the nurse to deliver inotropic drugs safely. Invasive blood pressure monitoring should be established before administering inotropic drugs, because of their rapid action. Inotropes should be administered via a central venous catheter. Drug administration procedures should be followed stringently.